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Magic Mushrooms 'Reboot' Brain In Depressed People, Study Suggests

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An anonymous reader quotes a report from The Guardian: Magic mushrooms may effectively "reset" the activity of key brain circuits known to play a role in depression, the latest study to highlight the therapeutic benefits of psychedelics suggests. Psychedelics have shown promising results in the treatment of depression and addictions in a number of clinical trials over the last decade. Imperial College London researchers used psilocybin -- the psychoactive compound that occurs naturally in magic mushrooms -- to treat a small number of patients with depression, monitoring their brain function, before and after. Images of patients' brains revealed changes in brain activity that were associated with marked and lasting reductions in depressive symptoms and participants in the trial reported benefits lasting up to five weeks after treatment. Dr Robin Carhart-Harris, head of psychedelic research at Imperial, who led the study, said: "We have shown for the first time clear changes in brain activity in depressed people treated with psilocybin after failing to respond to conventional treatments. Several of our patients described feeling 'reset' after the treatment and often used computer analogies. For example, one said he felt like his brain had been 'defragged' like a computer hard drive, and another said he felt 'rebooted.' Psilocybin may be giving these individuals the temporary 'kick start' they need to break out of their depressive states and these imaging results do tentatively support a 'reset' analogy. Similar brain effects to these have been seen with electroconvulsive therapy." The study has been published in Scientific Reports.

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orpheus17d
4 days ago
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Half the Universe's Missing Matter Has Just Been Finally Found

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An anonymous reader shares a report: The missing links between galaxies have finally been found. This is the first detection of the roughly half of the normal matter in our universe -- protons, neutrons and electrons -- unaccounted for by previous observations of stars, galaxies and other bright objects in space. You have probably heard about the hunt for dark matter, a mysterious substance thought to permeate the universe, the effects of which we can see through its gravitational pull. But our models of the universe also say there should be about twice as much ordinary matter out there, compared with what we have observed so far. Two separate teams found the missing matter -- made of particles called baryons rather than dark matter -- linking galaxies together through filaments of hot, diffuse gas. "The missing baryon problem is solved," says Hideki Tanimura at the Institute of Space Astrophysics in Orsay, France, leader of one of the groups. The other team was led by Anna de Graaff at the University of Edinburgh, UK. Because the gas is so tenuous and not quite hot enough for X-ray telescopes to pick up, nobody had been able to see it before.

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orpheus17d
8 days ago
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Saturday Morning Breakfast Cereal - Neighborhood

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Click here to go see the bonus panel!

Hovertext:
To be clear, I have no intention to talk to my neighbors. I just want to know what they're thinking.

New comic!
Today's News:

The Soonish book tour is nearly upon us! Come see me and Kelly and events around the US!

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orpheus17d
9 days ago
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Amazon Is Headed For the Prescription-Drug Market, Analysts Say

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An anonymous reader quotes a report from Bloomberg: Amazon.com Inc. is almost certain to enter the business of selling prescription drugs by 2019, said two analysts at Leerink Partners, posing a direct threat to the U.S.'s biggest brick-and-mortar drugstore chains. "It's a matter of when, not if," Leerink Partners analyst David Larsen said in a report to clients late Thursday. "We expect an announcement within the next 1-2 years." Amazon has a long standing interest in prescription drugs, an industry with multiple middlemen, long supply chains and opaque pricing. In the 1990s, it invested in startup Drugstore.com and Amazon Chief Executive Officer Jeff Bezos sat on the board. Walgreens eventually purchased the site and shuttered it last year to focus on its own branded website Walgreens.com. Leerink's calls with industry experts suggest that Amazon "is in active discussions" with mid-size pharmacy benefit managers and possibly larger player such as Prime Therapeutics, Larsen's colleague, Ana Gupte, wrote in a separate report Friday. On Friday, CNBC reported that Amazon could make a decision about selling prescription drugs online before Thanksgiving.

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orpheus17d
11 days ago
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Ancient Papyrus Finally Solves Egypt's 'Great Pyramid' Mystery

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schwit1 was the first Slashdot reader to bring us the news. Newsweek reports: Archaeologists believe they have found the key to unlocking a mystery almost as old as the Great Pyramid itself: Who built the structure and how were they able to transport two-ton blocks of stone to the ancient wonder more than 4,500 years ago...? Experts had long established that the stones from the pyramid's chambers were transported from as far away as Luxor, more than 500 miles to the south of Giza, the location of the Great Pyramid, but had never agreed how they got there. However, the diary of an overseer, uncovered in the seaport of Wadi al-Jafr, appears to answer the age-old question, showing the ancient Egyptians harnessed the power of the Nile to transport the giant blocks of stone. According to a new British documentary Egypt's Great Pyramid: The New Evidence, which aired on the U.K.'s Channel 4 on Sunday, the Great Pyramid, also known as the Pyramid of Khufu, was built using an intricate system of waterways which allowed thousands of workers to pull the massive stones, floated on boats, into place with ropes. Along with the papyrus diary of the overseer, known as Merer, the archaeologists uncovered a ceremonial boat and a system of waterworks. The ancient text described how Merer's team dug huge canals to channel the water of the Nile to the pyramid.

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orpheus17d
15 days ago
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Saturday Morning Breakfast Cereal - Hunting Man

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Click here to go see the bonus panel!

Hovertext:
I am prepared to read your emails on how I don't know how to pronounce 'pho.'

New comic!
Today's News:

Last full day to get in a proposal for BAHFest West!

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orpheus17d
32 days ago
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1 public comment
rosskarchner
30 days ago
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I would watch Friend or Pho
DC-ish
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